Product Data Sheet

Indoline

Catalog No. A51278

main product photo
Indoline is an indole derivative that functions as a key structure for CD4 mimetic compounds (CD4mcs), which facilitate conformational changes in the HIV-1 envelope glycoprotein (Env), leading to viral inactivation. This compound exhibits binding affinity for gp120 and has demonstrated the ability to inhibit HIV-1AD8 with an IC50 in the micromolar range. Indoline is valuable for research applications aimed at understanding and developing treatments for HIV-1 infection.
Chemical Information
Catalog NumA51278
M. Wt119.17
FormulaC8H9N
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.496-15-1
Synonyms
SMILESC12=C(NCC2)C=CC=C1
Biological Activity
DescriptionIndoline is an indole derivative that functions as a key structure for CD4 mimetic compounds (CD4mcs), which facilitate conformational changes in the HIV-1 envelope glycoprotein (Env), leading to viral inactivation. This compound exhibits binding affinity for gp120 and has demonstrated the ability to inhibit HIV-1AD8 with an IC50 in the micromolar range. Indoline is valuable for research applications aimed at understanding and developing treatments for HIV-1 infection.
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