Product Data Sheet

Claficapavir

Catalog No. A51308

main product photo
Claficapavir is a potent inhibitor of the HIV-1 nucleocapsid protein, specifically designed to interfere with its chaperone functions. With an IC50 of approximately 1 μM and a strong binding affinity (Kd = 20 nM), Claficapavir exhibits significant antiviral activity against HIV-1. This compound serves as a valuable tool for research focused on HIV pathogenesis and therapeutic interventions targeting viral replication.
Chemical Information
Catalog NumA51308
M. Wt393.86
FormulaC17H12ClNO4S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2055732-24-4
SynonymsA1752
SMILESO=C(N(C(S/1)=S)CCC(O)=O)C1=C\C2=CC=C(C3=CC=C(C=C3)Cl)O2
Biological Activity
DescriptionClaficapavir is a potent inhibitor of the HIV-1 nucleocapsid protein, specifically designed to interfere with its chaperone functions. With an IC50 of approximately 1 μM and a strong binding affinity (Kd = 20 nM), Claficapavir exhibits significant antiviral activity against HIV-1. This compound serves as a valuable tool for research focused on HIV pathogenesis and therapeutic interventions targeting viral replication.
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SHIPPING AND STORAGE
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