Product Data Sheet
Darunavir-d9
Catalog No. A51329
Darunavir-d9 is a stable isotope-labeled form of Darunavir, a next-generation HIV protease inhibitor. This compound exhibits significant antiviral activity against both wild-type and mutant HIV strains, displaying an IC50 of 0.003 μM and an IC90 of 0.009 μM while maintaining low cytotoxicity. Darunavir-d9 is primarily utilized in biochemical research applications, including drug metabolism studies and pharmacokinetics for advanced HIV research.
Chemical Information
| Catalog Num | A51329 |
|---|---|
| M. Wt | 556.72 |
| Formula | C27H28D9N3O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1133378-37-6 |
| Synonyms | TMC114-d9; UIC-94017-d9 |
| SMILES | O=C(O[C@@H]1[C@@]2([H])[C@@](OCC2)([H])OC1)N[C@@H](CC3=CC=CC=C3)[C@H](O)CN(S(=O)(C4=CC=C(N)C=C4)=O)C([2H])([2H])C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H] |
Biological Activity
| Description | Darunavir-d9 is a stable isotope-labeled form of Darunavir, a next-generation HIV protease inhibitor. This compound exhibits significant antiviral activity against both wild-type and mutant HIV strains, displaying an IC50 of 0.003 μM and an IC90 of 0.009 μM while maintaining low cytotoxicity. Darunavir-d9 is primarily utilized in biochemical research applications, including drug metabolism studies and pharmacokinetics for advanced HIV research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
