Product Data Sheet

SARS-CoV-IN-3

Catalog No. A51345

main product photo
SARS-CoV-IN-3 is a potent inhibitor of SARS-CoV replication, demonstrating anti-Coronavirus activity with an EC50 value of 3.6 μM in Vero cells. Additionally, it exhibits antimalarial properties against P. falciparum strains 3D7 and W2, with IC50 values of 11.7 nM and 20.4 nM, respectively. SARS-CoV-IN-3 also effectively mitigates HIV-1-induced cytopathic effects, yielding an EC50 of 10 μM in MT-4 cells. This compound is valuable for research in virology and parasitology.
Chemical Information
Catalog NumA51345
M. Wt469.74
FormulaC25H20ClFeN3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.888958-27-8
Synonyms
SMILESCCN(CCO)CC12=C3[Fe+2]145678(C9=C43)([C-]%10C5=C6C7=C8%10)[C-]29CNC%11=CC=NC%12=C%11C=CC(Cl)=C%12
Biological Activity
DescriptionSARS-CoV-IN-3 is a potent inhibitor of SARS-CoV replication, demonstrating anti-Coronavirus activity with an EC50 value of 3.6 μM in Vero cells. Additionally, it exhibits antimalarial properties against P. falciparum strains 3D7 and W2, with IC50 values of 11.7 nM and 20.4 nM, respectively. SARS-CoV-IN-3 also effectively mitigates HIV-1-induced cytopathic effects, yielding an EC50 of 10 μM in MT-4 cells. This compound is valuable for research in virology and parasitology.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.