Product Data Sheet
SARS-CoV-IN-2
Catalog No. A51347
SARS-CoV-IN-2 is a potent inhibitor of SARS-CoV replication, demonstrating anti-Coronavirus activity with an EC50 of 1.9 μM in Vero cells. Additionally, it exhibits significant inhibition of P. falciparum strains, showing IC50 values of 21.5 nM and 30 nM for the 3D7 and W2 strains, respectively. SARS-CoV-IN-2 also mitigates HIV-1-induced cytopathic effects, with an EC50 of 2.9 μM in MT-4 cells. This compound is valuable for research applications targeting both antiviral and antimalarial activities.
Chemical Information
| Catalog Num | A51347 |
|---|---|
| M. Wt | 455.72 |
| Formula | C24H18ClFeN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 888958-26-7 |
| Synonyms | |
| SMILES | CN(CCO)CC12=C3[Fe+2]1456789([C-]%10C6=C7C8=C9%10)[C-]2(C4=C53)CNC%11=CC=NC%12=C%11C=CC(Cl)=C%12 |
Biological Activity
| Description | SARS-CoV-IN-2 is a potent inhibitor of SARS-CoV replication, demonstrating anti-Coronavirus activity with an EC50 of 1.9 μM in Vero cells. Additionally, it exhibits significant inhibition of P. falciparum strains, showing IC50 values of 21.5 nM and 30 nM for the 3D7 and W2 strains, respectively. SARS-CoV-IN-2 also mitigates HIV-1-induced cytopathic effects, with an EC50 of 2.9 μM in MT-4 cells. This compound is valuable for research applications targeting both antiviral and antimalarial activities. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
