Product Data Sheet
NBD-14270
Catalog No. A51348
NBD-14270 is a potent HIV-1 entry antagonist that specifically targets the gp120 protein of the virus. With an IC50 of 180 nM, it exhibits significant antiviral activity against various HIV-1 Env-pseudotyped virus strains. Additionally, NBD-14270 demonstrates low cytotoxicity, with a CC50 exceeding 100 μM, making it a valuable candidate for research applications in HIV-1 inhibition.
Chemical Information
| Catalog Num | A51348 |
|---|---|
| M. Wt | 425.43 |
| Formula | C18H18F3N5O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2411819-82-2 |
| Synonyms | |
| SMILES | FC(F)(C1=CC=C(N=C1)C2=CC(C)=C(N2)C(N[C@H](C3=NC=C(S3)CO)CN)=O)F |
Biological Activity
| Description | NBD-14270 is a potent HIV-1 entry antagonist that specifically targets the gp120 protein of the virus. With an IC50 of 180 nM, it exhibits significant antiviral activity against various HIV-1 Env-pseudotyped virus strains. Additionally, NBD-14270 demonstrates low cytotoxicity, with a CC50 exceeding 100 μM, making it a valuable candidate for research applications in HIV-1 inhibition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
