Product Data Sheet
3′-Azido-2′,3′-dideoxyuridine
Catalog No. A51354
3′-Azido-2′,3′-dideoxyuridine is a nucleoside analog primarily targeting human immunodeficiency virus (HIV) replication. It exhibits significant antiviral activity in human peripheral blood mononuclear cells (PBMC) while demonstrating minimal toxicity to human bone marrow cells (BMC). In addition to its role as an HIV inhibitor, 3′-Azido-2′,3′-dideoxyuridine serves as a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Chemical Information
| Catalog Num | A51354 |
|---|---|
| M. Wt | 253.21 |
| Formula | C9H11N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 84472-85-5 |
| Synonyms | AzdU; AzddU; CS-87 |
| SMILES | OC[C@H]([C@@H](N=[N+]=[N-])C1)O[C@H]1N(C=C2)C(NC2=O)=O |
Biological Activity
| Description | 3′-Azido-2′,3′-dideoxyuridine is a nucleoside analog primarily targeting human immunodeficiency virus (HIV) replication. It exhibits significant antiviral activity in human peripheral blood mononuclear cells (PBMC) while demonstrating minimal toxicity to human bone marrow cells (BMC). In addition to its role as an HIV inhibitor, 3′-Azido-2′,3′-dideoxyuridine serves as a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
