Product Data Sheet
NBD-14189
Catalog No. A51385
NBD-14189 is a potent HIV-1 entry antagonist that demonstrates an IC50 of 89 nM against the HIV-1 HXB2 pseudovirus. This compound targets the HIV-1 gp120 protein, effectively inhibiting viral entry and showcasing notable antiviral activity with an EC50 of less than 200 nM. NBD-14189 is suitable for research applications focusing on HIV-1 entry mechanisms and antiviral drug development.
Chemical Information
| Catalog Num | A51385 |
|---|---|
| M. Wt | 428.40 |
| Formula | C18H16F4N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2234273-72-2 |
| Synonyms | |
| SMILES | FC1=C(C(F)(F)F)C=CC(C2=CC=C(C(N[C@@H](CN)C3=NC(CO)=CS3)=O)N2)=C1 |
Biological Activity
| Description | NBD-14189 is a potent HIV-1 entry antagonist that demonstrates an IC50 of 89 nM against the HIV-1 HXB2 pseudovirus. This compound targets the HIV-1 gp120 protein, effectively inhibiting viral entry and showcasing notable antiviral activity with an EC50 of less than 200 nM. NBD-14189 is suitable for research applications focusing on HIV-1 entry mechanisms and antiviral drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
