Product Data Sheet
GSK3532795 hydrochloride
Catalog No. A51395
GSK3532795 hydrochloride is a potent, orally bioavailable second-generation inhibitor targeting HIV-1 maturation. It demonstrates strong antiviral activity with EC50 values of 1.9 nM against HIV-1 wild type, 10.2 nM in human serum, and 2.7 nM and 13 nM for the HIV-1 V370A and ΔV370 variants, respectively. This compound is valuable for research applications focused on the pathogenesis and treatment of HIV-1 infections.
Chemical Information
| Catalog Num | A51395 |
|---|---|
| M. Wt | 727.48 |
| Formula | C42H63ClN2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2023808-13-9 |
| Synonyms | BMS-955176 hydrochloride |
| SMILES | CC1(C)C(C2=CC=C(C(O)=O)C=C2)=CC[C@@]3(C)[C@@]1([H])CC[C@]4(C)[C@]3([H])CC[C@@]5([H])[C@@]4(C)CC[C@]6(NCCN7CCS(CC7)(=O)=O)[C@]5([H])[C@H](C(C)=C)CC6.Cl |
Biological Activity
| Description | GSK3532795 hydrochloride is a potent, orally bioavailable second-generation inhibitor targeting HIV-1 maturation. It demonstrates strong antiviral activity with EC50 values of 1.9 nM against HIV-1 wild type, 10.2 nM in human serum, and 2.7 nM and 13 nM for the HIV-1 V370A and ΔV370 variants, respectively. This compound is valuable for research applications focused on the pathogenesis and treatment of HIV-1 infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
