GB-1a
Catalog No. A51505

GB-1a is a biflavanone that functions as an inhibitor of HIV-1 reverse transcriptase, demonstrating an IC50 value of 236 μM and an EC50 of 38.0 μM for HIV-1 replication. This compound effectively prevents the conversion of HIV-1 genomic RNA into DNA, making it a valuable tool for research on AIDS and HIV-1 infection. Additionally, GB-1a can be naturally sourced from the heartwood of Garcinia multiflora Champ, further emphasizing its potential for biological study.
Chemical Information
| Catalog Num | A51505 |
|---|---|
| M. Wt | 542.49 |
| Formula | C30H22O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19360-72-6 |
| Synonyms | Biflavanone GB-1a |
| SMILES | O=C1[C@@](C2=C3C(C(C[C@](C4=CC=C(C=C4)O)([H])O3)=O)=C(C=C2O)O)([H])[C@](C5=CC=C(C=C5)O)([H])OC6=CC(O)=CC(O)=C61 |
Biological Activity
| Description | GB-1a is a biflavanone that functions as an inhibitor of HIV-1 reverse transcriptase, demonstrating an IC50 value of 236 μM and an EC50 of 38.0 μM for HIV-1 replication. This compound effectively prevents the conversion of HIV-1 genomic RNA into DNA, making it a valuable tool for research on AIDS and HIV-1 infection. Additionally, GB-1a can be naturally sourced from the heartwood of Garcinia multiflora Champ, further emphasizing its potential for biological study. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


