Product Data Sheet
HIV-1 inhibitor-22
Catalog No. A51529
HIV-1 inhibitor-22 is a potent non-nucleoside reverse transcriptase (RT) inhibitor targeting HIV-1. It demonstrates significant antiretroviral activity, exhibiting IC50 values of 3.63 μM against HIV-1 RT and EC50 values of 0.304 μM and 0.201 μM against HIV-1 wild-type and K103N strains, respectively. Additionally, HIV-1 inhibitor-22 shows low cytotoxicity, with a CC50 greater than 227 μM, making it a valuable tool for investigating HIV-1 replication and resistance mechanisms in research applications.
Chemical Information
| Catalog Num | A51529 |
|---|---|
| M. Wt | 550.63 |
| Formula | C30H26N6O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2554618-33-4 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(C#N)C=C1)CSC2=NC(NC3=C(C)C=C(/C=C/C#N)C=C3C)=C4C=C(OC)C(OC)=CC4=N2 |
Biological Activity
| Description | HIV-1 inhibitor-22 is a potent non-nucleoside reverse transcriptase (RT) inhibitor targeting HIV-1. It demonstrates significant antiretroviral activity, exhibiting IC50 values of 3.63 μM against HIV-1 RT and EC50 values of 0.304 μM and 0.201 μM against HIV-1 wild-type and K103N strains, respectively. Additionally, HIV-1 inhibitor-22 shows low cytotoxicity, with a CC50 greater than 227 μM, making it a valuable tool for investigating HIV-1 replication and resistance mechanisms in research applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
