Product Data Sheet

HIV-1 inhibitor-14

Catalog No. A51573

main product photo
HIV-1 inhibitor-14 is a potent non-nucleoside reverse transcriptase (RT) inhibitor targeting HIV-1. It demonstrates strong inhibitory activity with an EC50 of 0.14 μM against HIV-1 RT and is effective against both wild-type and resistant strains, with EC50 values ranging from 5.79 to 28.3 nM. This compound is valuable for research applications focused on understanding HIV-1 resistance mechanisms and developing antiviral therapies.
Chemical Information
Catalog NumA51573
M. Wt560.67
FormulaC29H32N6O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2761172-65-8
Synonyms
SMILESCC1=CC(/C=C/C#N)=CC(C)=C1OC2=C3COCC3=NC(NC4CCN(CC4)C5=CC=C(C=C5)NS(=O)(C)=O)=N2
Biological Activity
DescriptionHIV-1 inhibitor-14 is a potent non-nucleoside reverse transcriptase (RT) inhibitor targeting HIV-1. It demonstrates strong inhibitory activity with an EC50 of 0.14 μM against HIV-1 RT and is effective against both wild-type and resistant strains, with EC50 values ranging from 5.79 to 28.3 nM. This compound is valuable for research applications focused on understanding HIV-1 resistance mechanisms and developing antiviral therapies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.