Product Data Sheet
U-89360E
Catalog No. A51575
U-89360E is a selective inhibitor of HIV-1 protease, demonstrating potent activity against the wildtype strain as well as the V82D and V82N mutants, with inhibitory constants (Ki) of 20 nM, 560 nM, and 2100 nM, respectively. Its effectiveness against multiple viral variants makes it a valuable tool for antiviral research and the development of therapeutic strategies targeting HIV-1. U-89360E is particularly relevant for studies focusing on resistance patterns and protease inhibition in the context of HIV treatment.
Chemical Information
| Catalog Num | A51575 |
|---|---|
| M. Wt | 596.76 |
| Formula | C28H52N8O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 161897-65-0 |
| Synonyms | |
| SMILES | N=C(N)NCCC[C@@H](C(N)=O)NC([C@H](CCC(N)=O)NC([C@H](C(C)C)C[C@H](O)[C@@H](NC(C)=O)CC1CCCCC1)=O)=O |
Biological Activity
| Description | U-89360E is a selective inhibitor of HIV-1 protease, demonstrating potent activity against the wildtype strain as well as the V82D and V82N mutants, with inhibitory constants (Ki) of 20 nM, 560 nM, and 2100 nM, respectively. Its effectiveness against multiple viral variants makes it a valuable tool for antiviral research and the development of therapeutic strategies targeting HIV-1. U-89360E is particularly relevant for studies focusing on resistance patterns and protease inhibition in the context of HIV treatment. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
