Product Data Sheet
HIV-1 inhibitor-23
Catalog No. A51576
HIV-1 Inhibitor-23 is a potent non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It exhibits effective inhibition with EC50 values of 24.9 nM for wild-type HIV-1 and 10.4 nM for the HIV-1 K103N mutant. Additionally, HIV-1 Inhibitor-23 demonstrates low cytotoxicity with a CC50 exceeding 221 μM and displays favorable stability in vitro under microsomal conditions, making it a valuable tool for HIV research and drug development.
Chemical Information
| Catalog Num | A51576 |
|---|---|
| M. Wt | 566.63 |
| Formula | C30H26N6O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2554622-28-3 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(C#N)C=C1)CS(C2=NC(NC3=C(C)C=C(/C=C/C#N)C=C3C)=C4C=C(OC)C(OC)=CC4=N2)=O |
Biological Activity
| Description | HIV-1 Inhibitor-23 is a potent non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It exhibits effective inhibition with EC50 values of 24.9 nM for wild-type HIV-1 and 10.4 nM for the HIV-1 K103N mutant. Additionally, HIV-1 Inhibitor-23 demonstrates low cytotoxicity with a CC50 exceeding 221 μM and displays favorable stability in vitro under microsomal conditions, making it a valuable tool for HIV research and drug development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
