Product Data Sheet

L 694746

Catalog No. A51577

main product photo
L 694746 is a potent inhibitor of HIV-1 protease, demonstrating an IC50 value of 1 nM and a Ki of 0.34 nM. This compound exhibits strong antiviral activity, making it a valuable reagent in the study of HIV replication and resistance mechanisms. Its effectiveness in inhibiting protease activity underscores its potential applications in HIV research and therapeutic development.
Chemical Information
Catalog NumA51577
M. Wt618.72
FormulaC35H42N2O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.139934-80-8
Synonyms
SMILESO=C(O)COC1=CC=C(C[C@@H](C(N[C@@H]2[C@H](O)CC3=C2C=CC=C3)=O)C[C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC4=CC=CC=C4)C=C1
Biological Activity
DescriptionL 694746 is a potent inhibitor of HIV-1 protease, demonstrating an IC50 value of 1 nM and a Ki of 0.34 nM. This compound exhibits strong antiviral activity, making it a valuable reagent in the study of HIV replication and resistance mechanisms. Its effectiveness in inhibiting protease activity underscores its potential applications in HIV research and therapeutic development.
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SHIPPING AND STORAGE
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