Product Data Sheet
DMJ-I-228
Catalog No. A51579
DMJ-I-228 is a CD4-mimetic compound that targets HIV-1 by binding to the gp120 protein within the conserved Phe 43 cavity, which is adjacent to the CD4-binding site. This interaction effectively obstructs the binding of CD4, leading to the inhibition of HIV-1 infection. DMJ-I-228 is utilized in research focused on HIV-1 entry mechanisms and the development of antiviral therapies.
Chemical Information
| Catalog Num | A51579 |
|---|---|
| M. Wt | 435.84 |
| Formula | C19H19ClFN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1374035-59-2 |
| Synonyms | |
| SMILES | O=CO.O=C(N[C@@H]1[C@@H](NC(N)=N)CC2=C1C=CC=C2)C(NC3=CC=C(Cl)C(F)=C3)=O |
Biological Activity
| Description | DMJ-I-228 is a CD4-mimetic compound that targets HIV-1 by binding to the gp120 protein within the conserved Phe 43 cavity, which is adjacent to the CD4-binding site. This interaction effectively obstructs the binding of CD4, leading to the inhibition of HIV-1 infection. DMJ-I-228 is utilized in research focused on HIV-1 entry mechanisms and the development of antiviral therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
