Product Data Sheet
5M038
Catalog No. A51582
5M038 is a potent inhibitor of HIV envelope-mediated fusion that targets the gp41 protein to prevent membrane fusion. By inhibiting the formation of the gp41 post-fusion conformation, 5M038 effectively disrupts viral infectivity and cell-cell fusion. Its broad-spectrum activity includes inhibition against multiple HIV-1 subtypes, including M and T strains, due to its binding to a highly conserved hydrophobic pocket within the gp41 trimer. This makes 5M038 a valuable tool for research in HIV fusion mechanisms and antiviral drug development.
Chemical Information
| Catalog Num | A51582 |
|---|---|
| M. Wt | 382.26 |
| Formula | C17H8F6N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 338962-32-6 |
| Synonyms | |
| SMILES | FC(F)(F)C1=C2C=CC3=NN=C(N3C2=NC(C(F)(F)F)=C1)C4=CC=CC=C4 |
Biological Activity
| Description | 5M038 is a potent inhibitor of HIV envelope-mediated fusion that targets the gp41 protein to prevent membrane fusion. By inhibiting the formation of the gp41 post-fusion conformation, 5M038 effectively disrupts viral infectivity and cell-cell fusion. Its broad-spectrum activity includes inhibition against multiple HIV-1 subtypes, including M and T strains, due to its binding to a highly conserved hydrophobic pocket within the gp41 trimer. This makes 5M038 a valuable tool for research in HIV fusion mechanisms and antiviral drug development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
