ZINC36617540
Catalog No. A51583

ZINC36617540 is a novel inhibitor targeting the Nef protein, demonstrating potent anti-HIV activity. It exhibits a strong binding affinity to the Nef protein and shares a comparable binding mode with the prototype molecule B9, as shown through molecular docking studies. The mechanism of action is primarily attributed to its hydrophobic and electrostatic interactions with the Nef protein, making it a valuable tool for HIV research and the development of antiviral therapeutics.
Chemical Information
| Catalog Num | A51583 |
|---|---|
| M. Wt | 355.39 |
| Formula | C21H17N5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1174905-91-9 |
| Synonyms | |
| SMILES | O=C1N(C(C)=NC2=C1C=CC=C2)/N=N/N(C3=CC=CC=C3)C4=CC=CC=C4 |
Biological Activity
| Description | ZINC36617540 is a novel inhibitor targeting the Nef protein, demonstrating potent anti-HIV activity. It exhibits a strong binding affinity to the Nef protein and shares a comparable binding mode with the prototype molecule B9, as shown through molecular docking studies. The mechanism of action is primarily attributed to its hydrophobic and electrostatic interactions with the Nef protein, making it a valuable tool for HIV research and the development of antiviral therapeutics. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


