Product Data Sheet
Nevirapine quinone methide
Catalog No. A51599
Nevirapine quinone methide is an active metabolite of Nevirapine, functioning as a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1. This compound is utilized in research to explore its antiviral properties and the mechanisms behind its associated toxicities, including severe skin and liver injuries resulting from its metabolic activation. Additionally, Nevirapine quinone methide has been identified as an inhibitor of CYP3A4, which may further elucidate its hepatic toxicity in studies focused on drug metabolism and safety.
Chemical Information
| Catalog Num | A51599 |
|---|---|
| M. Wt | 264.28 |
| Formula | C15H12N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1061160-22-2 |
| Synonyms | |
| SMILES | O=C1N=C2C(C=CN=C2N(C3CC3)C4=NC=CC=C14)=C |
Biological Activity
| Description | Nevirapine quinone methide is an active metabolite of Nevirapine, functioning as a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1. This compound is utilized in research to explore its antiviral properties and the mechanisms behind its associated toxicities, including severe skin and liver injuries resulting from its metabolic activation. Additionally, Nevirapine quinone methide has been identified as an inhibitor of CYP3A4, which may further elucidate its hepatic toxicity in studies focused on drug metabolism and safety. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
