Product Data Sheet
JE-2147
Catalog No. A51627
JE-2147 is a potent dipeptide inhibitor of HIV protease, exhibiting a Ki value of 0.33 nM for HIV-1 protease. This compound demonstrates effective antiviral activity against a broad range of HIV strains, including HIV-1, HIV-2, simian immunodeficiency virus, and various clinical isolates of HIV-1 in vitro. JE-2147 serves as a valuable tool for research into HIV protease inhibition and the development of antiretroviral therapies.
Chemical Information
| Catalog Num | A51627 |
|---|---|
| M. Wt | 575.72 |
| Formula | C32H37N3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 186538-00-1 |
| Synonyms | AG1776; KNI-764 |
| SMILES | CC(C=CC=C1)=C1CNC([C@H]2N(CSC2(C)C)C([C@@H](O)[C@@H](NC(C3=C(C(O)=CC=C3)C)=O)CC4=CC=CC=C4)=O)=O |
Biological Activity
| Description | JE-2147 is a potent dipeptide inhibitor of HIV protease, exhibiting a Ki value of 0.33 nM for HIV-1 protease. This compound demonstrates effective antiviral activity against a broad range of HIV strains, including HIV-1, HIV-2, simian immunodeficiency virus, and various clinical isolates of HIV-1 in vitro. JE-2147 serves as a valuable tool for research into HIV protease inhibition and the development of antiretroviral therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
