Product Data Sheet
APA-H-MPO hydrochloride
Catalog No. A51647
APA-H-MPO hydrochloride is an inhibitor of the PCAF bromodomain, specifically targeting its interaction with Tat-AcK50, making it a relevant compound in HIV research. This inhibitor has demonstrated the ability to effectively disrupt the binding of PCAF bromodomain to Tat-AcK50, which could hinder HIV replication. Preliminary cell studies indicate that APA-H-MPO hydrochloride exhibits low cytotoxicity, highlighting its potential as a therapeutic strategy to target host cell proteins involved in HIV pathogenesis.
Chemical Information
| Catalog Num | A51647 |
|---|---|
| M. Wt | 233.70 |
| Formula | C9H16ClN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1610362-93-0 |
| Synonyms | |
| SMILES | OCC1=CC=C([N+]([O-])=C1)NCCCN.[H]Cl |
Biological Activity
| Description | APA-H-MPO hydrochloride is an inhibitor of the PCAF bromodomain, specifically targeting its interaction with Tat-AcK50, making it a relevant compound in HIV research. This inhibitor has demonstrated the ability to effectively disrupt the binding of PCAF bromodomain to Tat-AcK50, which could hinder HIV replication. Preliminary cell studies indicate that APA-H-MPO hydrochloride exhibits low cytotoxicity, highlighting its potential as a therapeutic strategy to target host cell proteins involved in HIV pathogenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
