Product Data Sheet
I-XW-053 sodium
Catalog No. A51658
I-XW-053 sodium is an inhibitor of the HIV-1 capsid protein, demonstrating significant antiviral activity against HIV-189BZ167 with an IC50 value of 164.2 μM. This compound effectively disrupts the interaction between the N-terminal domains of the capsid protein, specifically at the NTD-NTD interface, exhibiting micromolar affinity. I-XW-053 is a valuable tool for research aimed at understanding HIV replication and developing therapeutic strategies against HIV infection.
Chemical Information
| Catalog Num | A51658 |
|---|---|
| M. Wt | 362.36 |
| Formula | C22H15N2NaO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1644644-89-2 |
| Synonyms | |
| SMILES | O=C(O[Na])C1=CC=C(C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2)C=C1 |
Biological Activity
| Description | I-XW-053 sodium is an inhibitor of the HIV-1 capsid protein, demonstrating significant antiviral activity against HIV-189BZ167 with an IC50 value of 164.2 μM. This compound effectively disrupts the interaction between the N-terminal domains of the capsid protein, specifically at the NTD-NTD interface, exhibiting micromolar affinity. I-XW-053 is a valuable tool for research aimed at understanding HIV replication and developing therapeutic strategies against HIV infection. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
