Product Data Sheet
HIV-1-IN-88
Catalog No. A51725
HIV-1-IN-88 is a potent HIV-1 protease inhibitor, demonstrating an IC50 value of 10 pM and an antiviral EC50 value of 10.4 nM. This compound retains efficacy against multidrug-resistant HIV-1 variants, including HIV-1Muta and HIV-1I50V, with EC50 values of 30.0 nM and 34.3 nM, respectively. HIV-1-IN-88 serves as a valuable tool for research aimed at understanding and combating HIV infection and resistance mechanisms.
Chemical Information
| Catalog Num | A51725 |
|---|---|
| M. Wt | 676.78 |
| Formula | C32H44N4O10S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2459707-59-4 |
| Synonyms | |
| SMILES | O[C@@H]([C@@H](NC([C@H](CC(N)=O)NC(O[C@@]1([C@]2([C@@]([H])(OC1)OCC2)[H])[H])=O)=O)CC3=CC=CC=C3)CN(CC(C)C)S(=O)(C4=CC=C(C=C4)OC)=O |
Biological Activity
| Description | HIV-1-IN-88 is a potent HIV-1 protease inhibitor, demonstrating an IC50 value of 10 pM and an antiviral EC50 value of 10.4 nM. This compound retains efficacy against multidrug-resistant HIV-1 variants, including HIV-1Muta and HIV-1I50V, with EC50 values of 30.0 nM and 34.3 nM, respectively. HIV-1-IN-88 serves as a valuable tool for research aimed at understanding and combating HIV infection and resistance mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
