Product Data Sheet
HI-346
Catalog No. A51749
HI-346 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1, exhibiting an IC50 value of 3 nM against the HIV-1 strain HTLV-IIIB. Additionally, HI-346 demonstrates spermicide activity with an EC50 of 42 μM while exhibiting no significant cytotoxicity to normal cells at effective concentrations. This compound is applicable for research in anti-HIV-1 therapies and contraceptive development.
Chemical Information
| Catalog Num | A51749 |
|---|---|
| M. Wt | 340.28 |
| Formula | C14H18BrN3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 149486-68-0 |
| Synonyms | |
| SMILES | BrC1=CC=C(NC(NCCC2=CCCCC2)=S)N=C1 |
Biological Activity
| Description | HI-346 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1, exhibiting an IC50 value of 3 nM against the HIV-1 strain HTLV-IIIB. Additionally, HI-346 demonstrates spermicide activity with an EC50 of 42 μM while exhibiting no significant cytotoxicity to normal cells at effective concentrations. This compound is applicable for research in anti-HIV-1 therapies and contraceptive development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
