Product Data Sheet
Oseltamivir acid-d3
Catalog No. A52005
Oseltamivir acid-d3 is a deuterium-labeled derivative of Oseltamivir acid, which serves as the active metabolite of Oseltamivir phosphate. This compound acts as a highly selective inhibitor of influenza virus neuraminidase, exhibiting an IC50 of 2 nM against both influenza A and B viruses. While its ability to cross the blood-brain barrier is limited under normal physiological conditions, penetration is notably increased during inflammatory states, making it a valuable reagent for studying antiviral mechanisms and neuroinflammation in research applications.
Chemical Information
| Catalog Num | A52005 |
|---|---|
| M. Wt | 287.37 |
| Formula | C14H21D3N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1242184-43-5 |
| Synonyms | GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3 |
| SMILES | O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C([2H])([2H])[2H])=O)[C@@H](N)C1)O |
Biological Activity
| Description | Oseltamivir acid-d3 is a deuterium-labeled derivative of Oseltamivir acid, which serves as the active metabolite of Oseltamivir phosphate. This compound acts as a highly selective inhibitor of influenza virus neuraminidase, exhibiting an IC50 of 2 nM against both influenza A and B viruses. While its ability to cross the blood-brain barrier is limited under normal physiological conditions, penetration is notably increased during inflammatory states, making it a valuable reagent for studying antiviral mechanisms and neuroinflammation in research applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
