Product Data Sheet
Cap-dependent endonuclease-IN-2
Catalog No. A52067
Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN), targeting the enzymatic activity crucial for the replication of various viruses, including influenza. This compound demonstrates a strong inhibitory effect on RNA polymerase activity in A viruses, making it a valuable tool for virology research. Notably, Cap-dependent endonuclease-IN-2 exhibits lower cytotoxicity and favorable pharmacokinetic properties in vivo, supporting its potential as an effective antiviral agent for further investigation.
Chemical Information
| Catalog Num | A52067 |
|---|---|
| M. Wt | 589.59 |
| Formula | C30H24FN3O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2303917-78-2 |
| Synonyms | |
| SMILES | COC(OCOC1=C2N(C=CC1=O)N([C@@]3([H])N(CCOC3)C2=O)[C@@]4([H])C5=CC=C(F)C=C5C6=C(SC=C6)C7=CC=CC=C74)=O |
Biological Activity
| Description | Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN), targeting the enzymatic activity crucial for the replication of various viruses, including influenza. This compound demonstrates a strong inhibitory effect on RNA polymerase activity in A viruses, making it a valuable tool for virology research. Notably, Cap-dependent endonuclease-IN-2 exhibits lower cytotoxicity and favorable pharmacokinetic properties in vivo, supporting its potential as an effective antiviral agent for further investigation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
