Product Data Sheet
Cap-dependent endonuclease-IN-5
Catalog No. A52070
Cap-dependent endonuclease-IN-5 is a selective inhibitor of cap-dependent endonuclease (CEN), a crucial enzyme in the lifecycle of the influenza virus. This compound demonstrates significant antiviral activity against influenza while exhibiting lower cytotoxicity compared to existing treatments. Additionally, Cap-dependent endonuclease-IN-5 shows improved pharmacokinetic and pharmacodynamic properties in vivo, making it a valuable tool for research on CEN-targeted antiviral therapies.
Chemical Information
| Catalog Num | A52070 |
|---|---|
| M. Wt | 553.60 |
| Formula | C27H21F2N3O4S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2416258-53-0 |
| Synonyms | |
| SMILES | O=C1N2[C@](COCC2)([H])N([C@@H]3C4=CC=C5C=C(C)SC5=C4SCC6=C(F)C(F)=CC=C36)N7C1=C(O)C(C=C7)=O |
Biological Activity
| Description | Cap-dependent endonuclease-IN-5 is a selective inhibitor of cap-dependent endonuclease (CEN), a crucial enzyme in the lifecycle of the influenza virus. This compound demonstrates significant antiviral activity against influenza while exhibiting lower cytotoxicity compared to existing treatments. Additionally, Cap-dependent endonuclease-IN-5 shows improved pharmacokinetic and pharmacodynamic properties in vivo, making it a valuable tool for research on CEN-targeted antiviral therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
