Product Data Sheet
Influenza virus-IN-4
Catalog No. A52105
Influenza virus-IN-4 is a potent inhibitor of the influenza virus neuraminidase, exhibiting IC50 values of 3.4 µM, 0.094 µM, 0.79 µM, and 0.077 µM against H5N1, H5N2, H5N6, and H5N8, respectively. This compound demonstrates effective NA-inhibitory activity, contributing to its role in antiviral research. Additionally, Influenza virus-IN-4 exhibits low cytotoxicity, with a CC50 greater than 200 µM, and displays no significant toxicity at doses of 1500 mg/kg in murine models. Its safety profile and efficacy in inhibiting neuraminidase make it a valuable tool for studying influenza virus pathogenesis and developing therapeutic strategies.
Chemical Information
| Catalog Num | A52105 |
|---|---|
| M. Wt | 418.50 |
| Formula | C23H31FN2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2133818-85-4 |
| Synonyms | |
| SMILES | O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](NC/C=C/C2=CC=C(F)C=C2)C1)O |
Biological Activity
| Description | Influenza virus-IN-4 is a potent inhibitor of the influenza virus neuraminidase, exhibiting IC50 values of 3.4 µM, 0.094 µM, 0.79 µM, and 0.077 µM against H5N1, H5N2, H5N6, and H5N8, respectively. This compound demonstrates effective NA-inhibitory activity, contributing to its role in antiviral research. Additionally, Influenza virus-IN-4 exhibits low cytotoxicity, with a CC50 greater than 200 µM, and displays no significant toxicity at doses of 1500 mg/kg in murine models. Its safety profile and efficacy in inhibiting neuraminidase make it a valuable tool for studying influenza virus pathogenesis and developing therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
