Product Data Sheet
Neuraminidase-IN-18
Catalog No. A52116
Neuraminidase-IN-18 is a potent neuraminidase inhibitor designed to target the neuraminidase enzyme in influenza viruses. It exhibits significant inhibitory activity against H5N1 neuraminidase, with IC50 values of 0.14 μM for the wild-type strain and 0.27 μM for the H5N1-H274Y mutant. This compound effectively inhibits influenza virus replication at the cellular level, making it a valuable tool for research in antiviral drug development and the study of influenza pathogenicity.
Chemical Information
| Catalog Num | A52116 |
|---|---|
| M. Wt | 423.46 |
| Formula | C22H18FN3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2935407-32-0 |
| Synonyms | |
| SMILES | O=C(CSC1=NN=C(COC2=CC3=C(C=CC=C3)C=C2)O1)NCC4=CC=C(C=C4)F |
Biological Activity
| Description | Neuraminidase-IN-18 is a potent neuraminidase inhibitor designed to target the neuraminidase enzyme in influenza viruses. It exhibits significant inhibitory activity against H5N1 neuraminidase, with IC50 values of 0.14 μM for the wild-type strain and 0.27 μM for the H5N1-H274Y mutant. This compound effectively inhibits influenza virus replication at the cellular level, making it a valuable tool for research in antiviral drug development and the study of influenza pathogenicity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
