Product Data Sheet
Urumin
Catalog No. A52178
Urumin is an antiviral peptide that targets the conserved stalk of H1 hemagglutinin, exhibiting potent antiviral activity against human influenza A virus. With an IC50 value of 3.8 μM against the PR8 strain, Urumin effectively inhibits the growth of both drug-sensitive and drug-resistant H1 influenza viruses. In preclinical studies, Urumin has demonstrated protective effects in naive mice against lethal influenza infection, highlighting its potential for therapeutic applications in influenza management.
Chemical Information
| Catalog Num | A52178 |
|---|---|
| M. Wt | 2961.34 |
| Formula | C129H198N42O35S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2215863-74-2 |
| Synonyms | |
| SMILES | C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CS)=O)C)=O)[C@H](CC)C)=O)C)=O)=O)CC(N)=O)=O)CO)=O)=O)CCCNC(=N)N)=O)=O)CS)=O)CCC(N)=O)=O)CO)=O)CC(O)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@H]([C@H](CC)C)N)=O)CCC4)CC(C)C)=O)CCCNC(=N)N)=O)=O)C)=O)=O)[C@H](CC)C)=O)CC(N)=O)=O)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6 |
Biological Activity
| Description | Urumin is an antiviral peptide that targets the conserved stalk of H1 hemagglutinin, exhibiting potent antiviral activity against human influenza A virus. With an IC50 value of 3.8 μM against the PR8 strain, Urumin effectively inhibits the growth of both drug-sensitive and drug-resistant H1 influenza viruses. In preclinical studies, Urumin has demonstrated protective effects in naive mice against lethal influenza infection, highlighting its potential for therapeutic applications in influenza management. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
