Product Data Sheet
G243-1720
Catalog No. A52207
G243-1720 is a potent anti-Orthopoxvirus agent that targets the OPG57 (F13) protein, inducing its dimerization. This broad-spectrum inhibitor effectively blocks the replication of various poxviruses while exhibiting no effect on non-poxviruses. G243-1720 disrupts the formation of extracellular membrane virus particles, thus preventing viral spread between cells. In murine models, G243-1720 significantly reduces the viral load of monkeypox virus (MPXV) in lung tissue, highlighting its potential for therapeutic application in poxvirus infections.
Chemical Information
| Catalog Num | A52207 |
|---|---|
| M. Wt | 437.98 |
| Formula | C21H28ClN3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 932311-85-8 |
| Synonyms | |
| SMILES | CC1=CC=C(C(Cl)=C1)NS(=O)(C2=C(N(C(C)=C2C(N3CCCCCC3)=O)C)C)=O |
Biological Activity
| Description | G243-1720 is a potent anti-Orthopoxvirus agent that targets the OPG57 (F13) protein, inducing its dimerization. This broad-spectrum inhibitor effectively blocks the replication of various poxviruses while exhibiting no effect on non-poxviruses. G243-1720 disrupts the formation of extracellular membrane virus particles, thus preventing viral spread between cells. In murine models, G243-1720 significantly reduces the viral load of monkeypox virus (MPXV) in lung tissue, highlighting its potential for therapeutic application in poxvirus infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
