Product Data Sheet

L-Canaline

Catalog No. A52256

main product photo
L-Canaline is a nonprotein amino acid primarily associated with leguminous plants. It acts as a potent and irreversible inhibitor of ornithine aminotransferase and exhibits cytotoxic properties. L-Canaline has demonstrated significant antiproliferative effects and inhibits the growth of the malaria parasite Plasmodium falciparum, with an IC50 value of 297 nM. This compound is valuable for research applications in cancer biology and metabolic studies involving endogenous metabolites.
Chemical Information
Catalog NumA52256
M. Wt134.13
FormulaC4H10N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.496-93-5
Synonyms
SMILESN[C@@H](CCON)C(O)=O
Biological Activity
DescriptionL-Canaline is a nonprotein amino acid primarily associated with leguminous plants. It acts as a potent and irreversible inhibitor of ornithine aminotransferase and exhibits cytotoxic properties. L-Canaline has demonstrated significant antiproliferative effects and inhibits the growth of the malaria parasite Plasmodium falciparum, with an IC50 value of 297 nM. This compound is valuable for research applications in cancer biology and metabolic studies involving endogenous metabolites.
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