Product Data Sheet
Columbin
Catalog No. A52297
Columbin is a bioactive diterpenoid furanolactone derived from Calumbae radix, known for its anti-inflammatory and anti-trypanosomal activities. It exhibits selective inhibition of COX-2 with an EC50 of 53.1 μM while showing significantly lower activity on COX-1 (EC50 of 327 μM). This compound is utilized in various research applications aimed at understanding inflammatory pathways and developing strategies against trypanosomiasis.
Chemical Information
| Catalog Num | A52297 |
|---|---|
| M. Wt | 358.39 |
| Formula | C20H22O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 546-97-4 |
| Synonyms | |
| SMILES | O=C1[C@](C=C2)(O)[C@@](CC3)(C)[C@@]([C@@](C[C@@H](C4=COC=C4)O5)(C)[C@]3([H])C5=O)([H])[C@]2([H])O1 |
Biological Activity
| Description | Columbin is a bioactive diterpenoid furanolactone derived from Calumbae radix, known for its anti-inflammatory and anti-trypanosomal activities. It exhibits selective inhibition of COX-2 with an EC50 of 53.1 μM while showing significantly lower activity on COX-1 (EC50 of 327 μM). This compound is utilized in various research applications aimed at understanding inflammatory pathways and developing strategies against trypanosomiasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
