Product Data Sheet
ACT-451840
Catalog No. A52332
ACT-451840 is a potent oral inhibitor specifically targeting Plasmodium falciparum, including both sensitive and resistant strains. This compound demonstrates significant activity against all asexual blood stages of the parasite, characterized by a rapid onset of action. ACT-451840 exhibits a mechanism of action akin to that of artemisinin derivatives, effectively facilitating the elimination of the malaria pathogen. It serves as a valuable research tool for studies related to malaria treatment and resistance.
Chemical Information
| Catalog Num | A52332 |
|---|---|
| M. Wt | 750.97 |
| Formula | C47H54N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1984890-99-4 |
| Synonyms | |
| SMILES | O=C(N(CC1=CC=C(N2CCN(C(C)=O)CC2)C=C1)[C@@H](CC3=CC=CC=C3)C(N4CCN(CC5=CC=C(C#N)C=C5)CC4)=O)/C=C/C6=CC=C(C(C)(C)C)C=C6 |
Biological Activity
| Description | ACT-451840 is a potent oral inhibitor specifically targeting Plasmodium falciparum, including both sensitive and resistant strains. This compound demonstrates significant activity against all asexual blood stages of the parasite, characterized by a rapid onset of action. ACT-451840 exhibits a mechanism of action akin to that of artemisinin derivatives, effectively facilitating the elimination of the malaria pathogen. It serves as a valuable research tool for studies related to malaria treatment and resistance. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
