Product Data Sheet
Flufenamic acid-13C6
Catalog No. A52360
Flufenamic acid-13C6 is a stable isotope-labeled derivative of Flufenamic acid, a non-steroidal anti-inflammatory agent. It primarily targets cyclooxygenase (COX) and activates AMP-activated protein kinase (AMPK), while also modulating various ion channels, including chloride and L-type Ca2+ channels, and non-selective cation channels. Additionally, Flufenamic acid-13C6 binds to the central pocket of TEAD2 YBD, inhibiting TEAD function and impacting TEAD-YAP-dependent biological processes, such as cell migration and proliferation. This compound is valuable for metabolic studies and investigations into inflammatory pathways.
Chemical Information
| Catalog Num | A52360 |
|---|---|
| M. Wt | 287.19 |
| Formula | C813C6H10F3NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1325559-30-5 |
| Synonyms | |
| SMILES | OC([13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=CC(C(F)(F)F)=CC=C2)=O |
Biological Activity
| Description | Flufenamic acid-13C6 is a stable isotope-labeled derivative of Flufenamic acid, a non-steroidal anti-inflammatory agent. It primarily targets cyclooxygenase (COX) and activates AMP-activated protein kinase (AMPK), while also modulating various ion channels, including chloride and L-type Ca2+ channels, and non-selective cation channels. Additionally, Flufenamic acid-13C6 binds to the central pocket of TEAD2 YBD, inhibiting TEAD function and impacting TEAD-YAP-dependent biological processes, such as cell migration and proliferation. This compound is valuable for metabolic studies and investigations into inflammatory pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
