Product Data Sheet

RYL-552S

Catalog No. A52400

main product photo
RYL-552S is a selective inhibitor of PfNDH2, a crucial enzyme in the electron transport chain of Plasmodium falciparum. This compound demonstrates potent efficacy against drug-resistant strains of the parasite, effectively eliminating asexual blood-stage forms in vitro. Its mechanism of action makes RYL-552S a valuable tool for studying antimalarial resistance and developing new therapeutic strategies.
Chemical Information
Catalog NumA52400
M. Wt443.46
FormulaC24H17F4NOS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1801444-69-8
Synonyms
SMILESO=C1C2=C(NC(C3=CC=C(CC4=CC=C(C=C4)SC(F)(F)F)C=C3)=C1C)C=CC=C2F
Biological Activity
DescriptionRYL-552S is a selective inhibitor of PfNDH2, a crucial enzyme in the electron transport chain of Plasmodium falciparum. This compound demonstrates potent efficacy against drug-resistant strains of the parasite, effectively eliminating asexual blood-stage forms in vitro. Its mechanism of action makes RYL-552S a valuable tool for studying antimalarial resistance and developing new therapeutic strategies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.