Product Data Sheet

Trypaflavin

Catalog No. A52500

main product photo
Trypaflavin is an acridine derivative recognized for its antileishmanial activity. It exerts its effects by targeting germ cells and inducing chromosomal aberrations in unfertilized oocytes, resulting in increased rates of genetic instability. Notably, Trypaflavin demonstrates significant toxicity toward Leishmania, leading to immediate lysis of leptomonads. This compound serves as a valuable tool in the study of leishmaniasis and related cellular processes.
Chemical Information
Catalog NumA52500
M. Wt259.73
FormulaC14H14ClN3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.86-40-8
Synonyms
SMILESC[N+]1=C2C=C(N)C=CC2=CC3=C1C=C(N)C=C3.[Cl-]
Biological Activity
DescriptionTrypaflavin is an acridine derivative recognized for its antileishmanial activity. It exerts its effects by targeting germ cells and inducing chromosomal aberrations in unfertilized oocytes, resulting in increased rates of genetic instability. Notably, Trypaflavin demonstrates significant toxicity toward Leishmania, leading to immediate lysis of leptomonads. This compound serves as a valuable tool in the study of leishmaniasis and related cellular processes.
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