Product Data Sheet
Closantel-13C6
Catalog No. A52626
Closantel-13C6 is a stable isotope-labeled form of Closantel, a halogenated salicylanilide known for its potent anti-parasitic properties. It selectively inhibits Onchocerca volvulus chitinase (OvCHT1) with an IC50 of 1.6 μM and a Ki of 468 nM, effectively disrupting the development of larvae from the L3 to L4 stage. This compound is valuable in research focused on treatments for river blindness and other helminth infections.
Chemical Information
| Catalog Num | A52626 |
|---|---|
| M. Wt | 669.03 |
| Formula | C1613C6H14Cl2I2N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1325559-20-3 |
| Synonyms | |
| SMILES | N#CC(C(C=C1)=CC=C1Cl)C(C=C2C)=C(C=C2NC([13C]([13CH]=[13C]3I)=[13C]([13C](I)=[13CH]3)O)=O)Cl |
Biological Activity
| Description | Closantel-13C6 is a stable isotope-labeled form of Closantel, a halogenated salicylanilide known for its potent anti-parasitic properties. It selectively inhibits Onchocerca volvulus chitinase (OvCHT1) with an IC50 of 1.6 μM and a Ki of 468 nM, effectively disrupting the development of larvae from the L3 to L4 stage. This compound is valuable in research focused on treatments for river blindness and other helminth infections. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
