Product Data Sheet
TCMDC-125457
Catalog No. A52654
TCMDC-125457 is a potent parasite modulator that induces calcium redistribution while minimally inhibiting heme crystallization. This compound has shown high efficacy in a single-dose combination with artesunate, particularly against tightly synchronized artemisinin-resistant ring-stage parasites. Its unique mechanism and activity position TCMDC-125457 as a valuable tool for research into antimalarial therapies and the understanding of drug resistance in parasitic infections.
Chemical Information
| Catalog Num | A52654 |
|---|---|
| M. Wt | 399.83 |
| Formula | C19H18ClN5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 872113-12-7 |
| Synonyms | |
| SMILES | ClC1=CC(NC(CN(C(C2=NN(N=C2)C3=CC=CC=C3)=O)C)=O)=C(C=C1)OC |
Biological Activity
| Description | TCMDC-125457 is a potent parasite modulator that induces calcium redistribution while minimally inhibiting heme crystallization. This compound has shown high efficacy in a single-dose combination with artesunate, particularly against tightly synchronized artemisinin-resistant ring-stage parasites. Its unique mechanism and activity position TCMDC-125457 as a valuable tool for research into antimalarial therapies and the understanding of drug resistance in parasitic infections. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
