Product Data Sheet
Antileishmanial agent-13
Catalog No. A52689
Antileishmanial agent-13 is a quinoline-isatin hybrid that functions as an effective antileishmanial agent targeting the L. major strain of Leishmania. This compound exerts its activity through an anti-folate mechanism, demonstrating potent inhibition against both promastigote and amastigote forms, with IC50 values of 0.604 μM and 0.508 μM, respectively. Its significant biological activity makes it a valuable reagent for research in Leishmaniasis treatment and drug development.
Chemical Information
| Catalog Num | A52689 |
|---|---|
| M. Wt | 401.64 |
| Formula | C17H10BrClN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 853725-86-7 |
| Synonyms | |
| SMILES | O=C1NC2=C(/C1=N\NC3=CC=NC4=CC(Cl)=CC=C43)C=C(C=C2)Br |
Biological Activity
| Description | Antileishmanial agent-13 is a quinoline-isatin hybrid that functions as an effective antileishmanial agent targeting the L. major strain of Leishmania. This compound exerts its activity through an anti-folate mechanism, demonstrating potent inhibition against both promastigote and amastigote forms, with IC50 values of 0.604 μM and 0.508 μM, respectively. Its significant biological activity makes it a valuable reagent for research in Leishmaniasis treatment and drug development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
