Product Data Sheet
NPD8790
Catalog No. A52737
NPD8790 is a selective inhibitor of mitochondrial respiratory complex I, exhibiting an IC50 of 2.4 µM in Caenorhabditis elegans. This compound demonstrates a high degree of selectivity for nematode mitochondria compared to those of humans, bovines, and mice. NPD8790 serves as an effective anthelmintic agent, targeting and eliminating adult soil-transmitted helminths, making it valuable in parasitology research and the development of new antiparasitic therapies.
Chemical Information
| Catalog Num | A52737 |
|---|---|
| M. Wt | 292.42 |
| Formula | C20H24N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 615281-26-0 |
| Synonyms | |
| SMILES | CC(CC1=CC=C(C=C1)C(C2=NC3=C(N2C)C=CC=C3)C)C |
Biological Activity
| Description | NPD8790 is a selective inhibitor of mitochondrial respiratory complex I, exhibiting an IC50 of 2.4 µM in Caenorhabditis elegans. This compound demonstrates a high degree of selectivity for nematode mitochondria compared to those of humans, bovines, and mice. NPD8790 serves as an effective anthelmintic agent, targeting and eliminating adult soil-transmitted helminths, making it valuable in parasitology research and the development of new antiparasitic therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
