Product Data Sheet
Anti-infective agent 9
Catalog No. A52796
Anti-infective agent 9 is an inhibitor of Plasmodium falciparum, exhibiting an IC50 of 600 nM, which targets metabolic pathways by downregulating pyruvate levels and interfering with the TCA cycle. This compound demonstrates favorable metabolic stability and low toxicity in human liver cells, making it a viable candidate for further research into antimalarial therapies. Additionally, studies suggest that its mechanism of action may involve pathways beyond 1-deoxy-D-xylulose-5-phosphate synthase (DXPS), highlighting its potential as a multifaceted therapeutic agent in combating malaria.
Chemical Information
| Catalog Num | A52796 |
|---|---|
| M. Wt | 356.39 |
| Formula | C14H11F3N4S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 758689-17-7 |
| Synonyms | |
| SMILES | CC1=C(SC(N)=N1)C2=CSC(NC3=CC=C(C=C3)C(F)(F)F)=N2 |
Biological Activity
| Description | Anti-infective agent 9 is an inhibitor of Plasmodium falciparum, exhibiting an IC50 of 600 nM, which targets metabolic pathways by downregulating pyruvate levels and interfering with the TCA cycle. This compound demonstrates favorable metabolic stability and low toxicity in human liver cells, making it a viable candidate for further research into antimalarial therapies. Additionally, studies suggest that its mechanism of action may involve pathways beyond 1-deoxy-D-xylulose-5-phosphate synthase (DXPS), highlighting its potential as a multifaceted therapeutic agent in combating malaria. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
