Product Data Sheet

Aphadilactone C

Catalog No. A52856

main product photo
Aphadilactone C is a selective inhibitor of diacylglycerol O-acyltransferase 1 (DGAT-1), exhibiting an IC50 of 0.46 μM. In addition to its DGAT-1 inhibition, Aphadilactone C demonstrates notable antimalarial properties with an IC50 value of 170 nM. This compound is valuable for research related to lipid metabolism and malaria treatment studies.
Chemical Information
Catalog NumA52856
M. Wt660.84
FormulaC40H52O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1522004-70-1
Synonyms
SMILESCC(C[C@H]1/C=C(C)/CCC[C@@]2(C(OC(C)3C)=CC3=O)C4=C(OC(C)(C4=O)C)[C@H](CC2)CCC/C(C)=C/[C@@H]5CC(C)=CC(O5)=O)=CC(O1)=O
Biological Activity
DescriptionAphadilactone C is a selective inhibitor of diacylglycerol O-acyltransferase 1 (DGAT-1), exhibiting an IC50 of 0.46 μM. In addition to its DGAT-1 inhibition, Aphadilactone C demonstrates notable antimalarial properties with an IC50 value of 170 nM. This compound is valuable for research related to lipid metabolism and malaria treatment studies.
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