Product Data Sheet
Vinclozolin M2
Catalog No. A52939
Vinclozolin M2 is an active metabolite of vinclozolin, primarily functioning as an antagonist of the mineralocorticoid receptor (IC50 = 1,400 nM) and the androgen receptor (IC50 = 0.17 nM). This compound is obtained through esterase activity and decarboxylation processes in C. elegans and human liver microsomes. Vinclozolin M2 exhibits significant biological activity, making it useful for investigating receptor-mediated signaling pathways and studying endocrine disruption in parasitic and mammalian systems.
Chemical Information
| Catalog Num | A52939 |
|---|---|
| M. Wt | 260.12 |
| Formula | C11H11Cl2NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 83792-61-4 |
| Synonyms | |
| SMILES | C=CC(C)(O)C(NC1=CC(Cl)=CC(Cl)=C1)=O |
Biological Activity
| Description | Vinclozolin M2 is an active metabolite of vinclozolin, primarily functioning as an antagonist of the mineralocorticoid receptor (IC50 = 1,400 nM) and the androgen receptor (IC50 = 0.17 nM). This compound is obtained through esterase activity and decarboxylation processes in C. elegans and human liver microsomes. Vinclozolin M2 exhibits significant biological activity, making it useful for investigating receptor-mediated signaling pathways and studying endocrine disruption in parasitic and mammalian systems. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
