Product Data Sheet
Isonicotinaldehyde 2-pyridin
Catalog No. A52983
Isonicotinaldehyde 2-pyridin is an antileishmanial compound targeting Leishmania species, particularly effective against the promastigotes of L. amazonensis and L. braziliensis. Its primary mechanism involves the enhancement of reactive oxygen species (ROS) production, leading to disruption of mitochondrial function in parasites. Notably, Isonicotinaldehyde 2-pyridin exhibits low toxicity to mouse macrophages, making it a promising candidate for further pharmacological studies in the treatment of leishmaniasis.
Chemical Information
| Catalog Num | A52983 |
|---|---|
| M. Wt | 198.22 |
| Formula | C11H10N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2241017-37-6 |
| Synonyms | |
| SMILES | C1(/C=N/NC2=NC=CC=C2)=CC=NC=C1 |
Biological Activity
| Description | Isonicotinaldehyde 2-pyridin is an antileishmanial compound targeting Leishmania species, particularly effective against the promastigotes of L. amazonensis and L. braziliensis. Its primary mechanism involves the enhancement of reactive oxygen species (ROS) production, leading to disruption of mitochondrial function in parasites. Notably, Isonicotinaldehyde 2-pyridin exhibits low toxicity to mouse macrophages, making it a promising candidate for further pharmacological studies in the treatment of leishmaniasis. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
