Product Data Sheet
ML471
Catalog No. A53085
ML471 is an orally active inhibitor of parasite tyrosyl-tRNA synthetase (PfTyrRS), which is essential for protein synthesis in Plasmodium species. This compound exhibits potent activity against malaria by selectively targeting PfTyrRS, providing valuable insights into the treatment of malaria infections. It is a useful tool for researchers investigating novel antimalarial strategies and exploring the role of tRNA synthetases in parasitic biology.
Chemical Information
| Catalog Num | A53085 |
|---|---|
| M. Wt | 388.40 |
| Formula | C13H20N6O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2226227-77-4 |
| Synonyms | |
| SMILES | CC(C)C1=NN([C@@H]2O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]2O)C3=NC=NC(N)=C31 |
Biological Activity
| Description | ML471 is an orally active inhibitor of parasite tyrosyl-tRNA synthetase (PfTyrRS), which is essential for protein synthesis in Plasmodium species. This compound exhibits potent activity against malaria by selectively targeting PfTyrRS, providing valuable insights into the treatment of malaria infections. It is a useful tool for researchers investigating novel antimalarial strategies and exploring the role of tRNA synthetases in parasitic biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
