Product Data Sheet
RSV L-protein-IN-1
Catalog No. A53166
RSV L-protein-IN-1 is a potent inhibitor of Respiratory Syncytial Virus (RSV) that targets viral polymerase with an IC50 of 0.089 μM. It effectively disrupts RSV mRNA synthesis by inhibiting the guanylation of viral transcripts, demonstrating an EC50 of 0.021 μM. In addition to its antiviral activity, RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM in HEp-2 cells) and has been shown to lower virus titers in mouse models of RSV infection, making it suitable for research applications aimed at understanding RSV pathogenesis and developing therapeutic strategies.
Chemical Information
| Catalog Num | A53166 |
|---|---|
| M. Wt | 600.66 |
| Formula | C32H36N6O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 851658-10-1 |
| Synonyms | |
| SMILES | O=C(C(C)(C)C1=C2C3=C(NC(C4=CC=C(C)C([N+]([O-])=O)=C4)=N3)C(N)=C1)N(CCCNCCC5=CC=C(OC)C(OC)=C5)C2=O |
Biological Activity
| Description | RSV L-protein-IN-1 is a potent inhibitor of Respiratory Syncytial Virus (RSV) that targets viral polymerase with an IC50 of 0.089 μM. It effectively disrupts RSV mRNA synthesis by inhibiting the guanylation of viral transcripts, demonstrating an EC50 of 0.021 μM. In addition to its antiviral activity, RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM in HEp-2 cells) and has been shown to lower virus titers in mouse models of RSV infection, making it suitable for research applications aimed at understanding RSV pathogenesis and developing therapeutic strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
