Product Data Sheet
MAC-5576
Catalog No. A53349
MAC-5576 is a potent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 of 81 nM. Additionally, it inhibits HAV 3C protease and thrombin with IC50 values of 0.5 μM and 13 μM, respectively. This compound serves as a valuable tool for research into antiviral therapies and protease inhibition mechanisms, particularly in the context of COVID-19. Its profile supports investigations into viral replication and potential therapeutic strategies.
Chemical Information
| Catalog Num | A53349 |
|---|---|
| M. Wt | 239.68 |
| Formula | C10H6ClNO2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 219929-01-8 |
| Synonyms | |
| SMILES | O=C(C1=CC=CS1)OC2=CC(Cl)=CN=C2 |
Biological Activity
| Description | MAC-5576 is a potent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 of 81 nM. Additionally, it inhibits HAV 3C protease and thrombin with IC50 values of 0.5 μM and 13 μM, respectively. This compound serves as a valuable tool for research into antiviral therapies and protease inhibition mechanisms, particularly in the context of COVID-19. Its profile supports investigations into viral replication and potential therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
