Product Data Sheet
RU-0415529
Catalog No. A53364
RU-0415529 is an orally bioavailable inhibitor targeting SARS-CoV-2 nonstructural protein 14 (NSP14), with an IC50 value of 356 nM. This compound effectively binds to the SAH-stabilized cap binding pocket, disrupting viral RNA methylation and subsequent viral replication. RU-0415529 demonstrates potent anti-infectious activity in mouse models, making it a valuable tool for research on SARS-CoV-2 virology and potential therapeutic applications.
Chemical Information
| Catalog Num | A53364 |
|---|---|
| M. Wt | 419.54 |
| Formula | C21H29N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1358734-35-6 |
| Synonyms | |
| SMILES | CC1CCN(S(=O)(C2=C(C)N(C)C(C(NCC3=CC=CC=C3OC)=O)=C2)=O)CC1 |
Biological Activity
| Description | RU-0415529 is an orally bioavailable inhibitor targeting SARS-CoV-2 nonstructural protein 14 (NSP14), with an IC50 value of 356 nM. This compound effectively binds to the SAH-stabilized cap binding pocket, disrupting viral RNA methylation and subsequent viral replication. RU-0415529 demonstrates potent anti-infectious activity in mouse models, making it a valuable tool for research on SARS-CoV-2 virology and potential therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
