Product Data Sheet
SARS-CoV-2 nsp13-IN-6
Catalog No. A53376
SARS-CoV-2 nsp13-IN-6 is a selective inhibitor of the non-structural protein 13 (nsp13) of SARS-CoV-2, demonstrating IC50 values of 27 μM and 33 μM for single-stranded DNA-dependent ATPase activity. This compound serves as a valuable tool for investigating the mechanisms of SARS-CoV-2 replication and offers potential applications in the development of therapeutic strategies against COVID-19. Its inhibition of nsp13 highlights its relevance in antiviral research aimed at disrupting viral replication.
Chemical Information
| Catalog Num | A53376 |
|---|---|
| M. Wt | 421.47 |
| Formula | C21H19N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 951588-85-5 |
| Synonyms | |
| SMILES | COC1=CC2=C(C=C1)N=C(NC(CN3C=NC4=NC(CCCC5)=C5C=C4C3=O)=O)S2 |
Biological Activity
| Description | SARS-CoV-2 nsp13-IN-6 is a selective inhibitor of the non-structural protein 13 (nsp13) of SARS-CoV-2, demonstrating IC50 values of 27 μM and 33 μM for single-stranded DNA-dependent ATPase activity. This compound serves as a valuable tool for investigating the mechanisms of SARS-CoV-2 replication and offers potential applications in the development of therapeutic strategies against COVID-19. Its inhibition of nsp13 highlights its relevance in antiviral research aimed at disrupting viral replication. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
